Operant Assessment of DMTP Spatial Working Memory in Mice

Rehearsal in spatial working memory.

This article reports 3 experiments that tested a hypothesis regarding the nature of rehearsal in spatial working memory, one in which discrete shifts of spatial selective attention mediate the maintenance of location-specific representations. Experiment 1 demonstrated increases in visual processing efficiency for locations held in working memory, which suggested that attention was oriented towa...

Visuo-spatial Working Memory

The Effects of Spark Training on Visual-Spatial Working Memory Operation in Children with Mental Retardation

Introduction: Mental retarded children who receive a wide range of health services, representing more than two percent of the population. Mental retardation is associated with significant constraints on mental performance and adaptive behavior as well as perceptual and practical skills. According to the studies, one of the important tools that can affect cognitive abilities, such as memory, is ...

Working memory and reference memory tests of spatial navigation in mice (Mus musculus).

Researchers in spatial cognition have debated for decades the specificity of the mechanisms through which spatial information is processed and stored. Interestingly, although rodents are the preferred animal model for studying spatial navigation, the behavioral methods traditionally used to assess spatial memory do not effectively test the predictions of specificity in their representation. To ...

CB2 Cannabinoid Receptor Knockout in Mice Impairs Contextual Long-Term Memory and Enhances Spatial Working Memory

Neurocognitive effects of cannabinoids have been extensively studied with a focus on CB1 cannabinoid receptors because CB1 receptors have been considered the major cannabinoid receptor in the nervous system. However, recent discoveries of CB2 cannabinoid receptors in the brain demand accurate determination of whether and how CB2 receptors are involved in the cognitive effects of cannabinoids. C...